Friday, March 18, 2011

Friday, March 18 Lectures

Ramo

LEADS        MI                       CA
I, AVL           Lateral                Circumflex
II,III, AVF       Inferior                RCA
V1-V4          Anterior              LAD
V5-V6          Antero-Lateral   LAD/Circumflex
MCL1*         Anterior              LAD
V3, V4         RV                       RCA

* analogous to lead V1

Valenzuela
inotropic versus ionotropic - ionotropic refers to ligand gated ion channels (see Partridge lecture); e.g., nicotinic receptor, GABA receptor. 

Inotropic refers to force of contraction of cardiac myocytes.  agents that increase intracellular calcium are positive inotropic agents.


Resta

M2 receptors and Autonomic Innervation of the Heart
p. 231, 233, to clarify point raised in lecture: In human hearts there is lots of sympathetic innervation of the ventricle but parasympathetic innervation is sparse.  this means the major effect of parasympathetic stimulation is on automaticity but not contractility. 

No comments:

Post a Comment