Thursday, April 21, 2011

April 21 Lectures

Fisher

Rondon (case wrap up)

Beta agonists used to treat hyperkalemia can cause tremor.  This is enhanced physiological tremor (normal tremor in everyone is enhanced) via the action of beta agonists on muscle spindles

1 lactic acid = 1 proton + 1 lactate
1 proton + 1 HCO3 = reduction of   HCO3 = anion gap increases by 1
AG went up by 14 but bicarb only went down by 11.  conclusion = extra metabolic alkalosis. 

also extra respiratory acidosis (PCO2 > predicted from Winter's formula)

Mary Widow  "anemia of inflammation"  -  inflammation causes liver to produce Hepcidin which prevents mobiliztion of iron from iron stores.  Proton pump inhibitors (omeprazole) caused ATN.

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