Tx for hypertension
Ca channel blockers (e.g., verapamil) and K channel activators (e.g., minoxadil) dilate vascular smooth muscle.
circulating norepinephrine versus circulating epinephrine
epi = increased cardiac output and vasodilation in muscle and liver (beta 2) Pressure does not change since increase in Q is balanced by decrease in R (P = QR)
circulating norepi causes increased cardiac output (beta 1) and increased vascular resistance from vasoconstriction in most arteries and veins (alpha 1 and 2). transient increase in heart rate is reduced via baroreceptor reflex.
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