Inbar
depolarization is phase 0, not phase 1. check your notes on this.
8.5 x 11 standard EKG paper is 10 seconds of time for rhythm strip. can use this to quickly calculate heart rate; no. of beats in rhythm strip x 60 = BPM.
Krinsky
p. 152; Textbooks definition of Cor Pulmonale: "Cor pulmonale is defined as an alteration in the structure and function of the right ventricle caused by a primary disorder of the respiratory system."
cardiomegaly = increased size or weight (or both)
intercalated disks = gap junctions
p. 152; pressure load leads to hypertrophy; volume load leads to dilation of heart.
findings at autopsy after first and fatal MI: no morphologic or histologic changes (but vessels may look bad); subsequent fatal heart attack reveals morphologic and histologic changes that took days to weeks to develope. Microvascular injury mainly occurs during reperfusion rather than ischemia. This injury is caused by the reintroduction of oxygen and subsequent formation of superoxide radicals.
p. 157; restrictive cardiomyopathy = decrease in compliance of ventricle. compliance = dV/dP. decreased compliance = stiffer ventricle = diastolic heart failure. also see p. 162 - constrictive pericarditis = decreased compliance.
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