Thursday, March 17, 2011

March 17 Lectures

Inbar

p. 195; rate of change in electrolyte disturbances often more important than absolute values.
Nernst equation is a bit easier to manage if you use the version

Em = -61 log [K]in/[K]out  since K is always higher inside than outside, the math is a bit easier.  answer is the same.   -61 = RT/ZF.  the reason hypothermia doesn't really change resting membrane potential is that T is absolute temperature (not Farenheit or centigrade) so it doesn't change much with hypothermia.
p. 195 & 196 intracellular shifts of potassium important in acidosis, beta blockers, glucose levels.
see Costanzo, p. 277, showing this figure:

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