Wednesday, March 23, 2011

March 23 Lectures

Resta

p. 302 bottom left.  ACh not physiologically important except in the few areas of the body where arterioles have parasympathetic innervation (salivary glands, gastrointestinal glands, and in genital erectile tissue.)

Vascular smooth muscle tone - big picture (you can fill in details from today's lectures):


"How does NO inhibit platelet aggregation?"  NO diffuses across platelet membrane and activates guanyl cyclase which induces formation of cGMP and cAMP which both inhibit aggregation and adhesion of platelets by multiple mechansism including decreasing expression of fibrinogen receptors.  







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