April 29 Lecture

Bryce

vasculitis symptoms - fatigue, fever, weight loss

medium vessels:  Kawasaki's disease - vasculitis - usually of coronary arteries.  80% of patients < 4 years old.  viral trigger.  most common among children of Japanese and Korean descent.

small vessels: 

• Wegener granulomatosis - granulomas with necrosis and vasculitis
• Churg-Strauss syndrome - associated with asthma - allergic vasculitis

vein diseases

Spaulding

ABC rule - PQR                P = QR

hypotension = systolic BP < 90 mm Hg

shock = MAP < 60 mm Hg

1. cardiogenic
2. hypovolemic
3. vasodilation

Big picture    P = QR       decreased P = dec Q and/or dec R

• if decQ (cardiogenic, hypovolemic) then compensation is inc R (vasoconstriction)   (pale, cold skin)
• 
  
• if decR (e.g., septic, anaphylactic) then compensation is inc Q (tachycardia, SNS) (warm skin)